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US EPA evaluates and registers pesticides for use and sale in the United States. After EPA has registered a product, it must also be registered in Ohio before it is legal to sell and use. Manufacturers are required to register their products in Ohio annually by submitting the application, fee, product label and MSDS. Registrations must be postmarked by June 30, of the registration year if distributed in Ohio. If a renewal or unregister product application is received after the deadline, the applicant must pay a 50% penalty fee of $75.00 per product as stated in the pesticide law.